Characterization and evaluation of antimicrobial activity of composite blends of aloevera extract and eugenol loaded Polyhydroxyalkanoate (PHA)

Abstract

Srividya Shivakumar*

Greece, Egypt, India, Mexico, Japan, and China are just a few of the civilizations that have employed Aloe vera for therapeutic reasons for millennia. Nefertiti and Cleopatra, two Egyptian queens, employed it as a regular component of their beauty regimens. It was used to cure soldiers' wounds by Alexander the Great and Christopher Columbus. Since Poly3-hydroxybutyrate (PHB) is biodegradable, effective in wet conditions, and includes an antibiotic element that is efficient against bacteria that cause skin infections. It is observed that by using these antimicrobial PHB blends in place of regular bandages have a better wound healing ability and have potential to reduce bio burden. In this paper, the methodology includes the application of PHB as a bio-based chemical, and the films have the potential to provide intriguing alternatives for used materials. Additionally, an attempt was made for different plant-based extracts to examine for a greater influence on skin-borne allergies, swelling tests, protein absorption investigations, etc. in order to establish the mechanical features of medicinal technique incorporated films and their role in enhancing wound healing capacity. It may also be possible to reduce the cost of such films by combining them with other biopolymers, such starch, to make them more practical and hence acceptable in everyday life.